The human microbiome represents an expansive realm of both recognized and undiscovered microscopic entities, engaged in countless biochemical changes along metabolic pathways that remain uncharted.
A multitude of microorganisms, encompassing bacteria, viruses, and fungi, interact with human physiology, surpassing the count of human cells. Predominantly, these microorganisms are “beneficial,” contributing to the prevention of issues caused by disease-inducing pathogens. Although pathogenic microorganisms sporadically lead to acute ailments and contribute to chronic conditions.
However, occasionally even the harmonious inhabitants, termed commensal microorganisms, shift into detrimental proportions. Such imbalances, deemed dysbiosis, occur whenever the proportions are believed to be detrimental. Dysbiosis is presumed to drive inflammation and autoimmune disorders.
Research is swiftly documenting diverse microbial populations linked to conditions like autism spectrum disorder, Parkinson’s disease, Crohn’s Disease, Alzheimer’s disease, multiple cancers, cardiovascular disease, and others.
Given the escalating incidence of diseases, the notion of a wholesome microbiome presents itself as a potential remedy. This perhaps explains the embrace of innovative ideas such as fecal transplants, where donor stool reintroduces beneficial gut bacteria, or even a synthetic microbiome cultured in a laboratory.
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