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Researched Nutritionals: HistaQuel

What Dr. Jess Loves:

This is a great product for mast cell activation syndrome or histamine intolerance. HistaQuel is a comprehensive formula providing a multi-faceted, systemic approach to supporting an overactive immune system

What is a mast cell?

Mast cells are part of the immune system and are primarily responsible for generating and releasing histamine in the body. Under typical conditions, this is a natural function of a healthy body working to rid itself of an allergen. However, mast cells can become overactive, releasing a cascade of histamine throughout the body, which results in heightened or continuous allergy symptoms.

Many allergy support supplements, such as diamine oxidase (DAO), focus on reducing histamine within the gut by utilizing enzymes to degrade the histamine. Unfortunately, this means they are limited in their function and only effective for reducing ingested histamine (i.e., histamine introduced to the body through the food we eat) within the GI tract. However, mast cells release histamine systemically. Therefore, when mast cells are activated, they release histamine throughout the body. Enzymes such as DAO do nothing to address the healthy function of mast cells or support the body’s healthy response to histamine and therefore serve limited benefit.

How does HistaQuel® support mast cell health?

HistaQuel® utilizes a comprehensive approach to support healthy mast cell function and histamine response systemically.* Seven clinically researched flavonoids and herbs have been combined to promote healthy levels of histamine production and healthy levels of histamine absorption.* This holistic approach resulted in a comprehensive formula featuring dual mechanisms of action.

Dual Mechanisms of Action

  • Promotes a healthy amount of histamine release by supporting healthy mast cell function*
  • Supports healthy level of histamine absorption by blocking histamine receptors (via competitive inhibition)*

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